Categories
Cardiológicos
CARDIAL
description
Mixed vasodilator and cardiac protector in tablets for oral administration.
presentation
Cases containing 3 blisters with 10 tablets .
action
Enalapril, an angiotensin converting enzyme inhibitor and mixed vasodilator, associated with spironolactone as cardiac protector to the effects of aldosterone.
indications
Heart failure in dogs due to valve insufficiency or dilated cardiomyopathy .
formula
Each tablet contains:
Enalapril base (as maleate) 5 mg
Spironolactone 5 mg
Excipients q.s.
dosage and administration
Dogs: 0.25 to 0.5 mg per kg of body weight every 12 or 24 h for life.
contraindications
Serious renal failure and systemic arterial hypotension. It should not be used in association with potassium sparing diuretics due to the risk of causing hyperkalemia. Pregnant and lactating bitches.
collateral damage
Anorexia, vomiting, drowsiness, lethargy, lack of coordination, hypotension, azotemia. Reversible prostatic atrophy is frequently seen in non-neutered males.
restrictions on use
Spironolactone has an antiandrogenic effect, so its administration is not recommended in growing dogs.
Caution
Monitor renal function before and during treatment.