Antibióticos

FLOXADAY COMPRIMIDOS

ADMINISTRATION ORAL

description

Broad-spectrum oral fluoroquinolone-based antibiotic .

presentation

Package containing 1 blister with 10 tablets .

action

Potent antibiotic activity. It shows superior activity against gram-negative, gram-positive, anaerobic and intracellular microorganisms (E. Coli and other enterobacteria, Pseudomona aeruginosa, Pasteurella spp., Bordetella bronchiseptica, Staphylococcus spp., Mycoplasma, Chlamydia/Chlamydophila spp). It interferes in the bacterial DNA synthesis, inhibiting two important enzymes:

Topoisomerase II (DNA gyrase): responsible for the relaxation of supercoiled DNA during transcription.
Topoisomerase IV: it intervenes in the separation of chromosomal DNA during cell division.

indications

It is especially developed to attack infections of:
Skin (pyoderma)
Soft tissues
Upper and lower airways
Urinary tract
Mammary glands
Bone (osteomyelitis)
ProstateSepticemia

formula

Each tablet contains:
Levofloxacin 100 mg, 200 mg and 400 mg according to package supplied.
Excipients q.s.

dosage and administration

Dogs: 10 mg of levofloxacin per kg of body weight, equivalent to one tablet every 10, 20 or 40 kg of body weight depending on the package supplied, by oral route every 24 hs. The peak concentration is reached 1 hour post–administration. Its bioavailability is 60- 70%. Treatment duration will vary based on the disease and the physician's indication.

contraindications

Contraindicated in animals with hypersensitivity to fluoroquinolones. Do not administer in pregnant or lactating bitches.

restrictions on use

Growing animals. Renal failure.