Antibióticos

FLOXADAY INYECTABLE

ADMINISTRATION INJECTABLE

description

Broad-spectrum fluoroquinolone-based antibiotic for injection .

presentation

50 mL vial.

action

Potent antibiotic activity. It shows superior activity on gram-negative, gram-positive, anaerobic and intracellular microorganisms (E. Coli and other enterobacteria, Pseudomona aeruginosa, Pasteurella spp., Bordetella bronchiseptica, Staphylococcus spp., Mycoplasma, Chlamydia/Chlamydophila spp).

It interferes in the bacterial DNA synthesis, inhibiting two important enzymes:
Topoisomerase II (DNA gyrase): responsible for the relaxation of supercoiled DNA during transcription.
Topoisomerase IV: it intervenes in the separation of chromosomal DNA during cell division.

indications

It is especially developed to attack infections of:

Skin (pyoderma)
Soft tissues
Upper and lower airways
Urinary tract
Mammary glands
Bone (osteomyelitis)
Prostate Septicemia

formula

100 mL of solution contains:
Levofloxacin 5 g
Excipients q.s.

dosage and administration

Dogs: 7.5 mg of levofloxacin per kg of body weight, equivalent to 1.5 mL every 10 kg of body weight every 24 hours. The peak concentration is reached 2 hours post–administration. Bioavailability of 90% and wide tissue distribution due to its liposolubility. Treatment duration will depend on the disease and the physician's indication.

contraindications

Contraindicated in animals with hypersensitivity to fluoroquinolones. Do not administer in pregnant or lactating bitches.

restrictions on use

Growing animals. Renal failure.