Mixed vasodilator with cardioprotective propertiesbased on enalapril and spironolactone. Tablets for dogs.
Cases containing 3 blisters with 10 tablets .
Enalapril is an angiotensin converting enzyme inhibitor and mixed vasodilator associated with spironolactone for cardioprotection against the effects of aldosterone.
Heart failure in dogs due to valve insufficiency or dilated cardiomyopathy.
Each tablet contains:
Enalapril 5 mg.
Spironolactone 5 mg.
Excipients q.s.
Enalapril 0.25 to 0.50 mg every 12 or 24 hours for life (equivalent to 1 tablet per 20 or 10 kg, respectively).
Serious renal failure and systemic arterial hypotension. It should not be used in association with potassium sparing diuretics due to the risk of causing hyperkalemia. Pregnant and lactating females.
Anorexia, vomiting, drowsiness, lethargy, lack of coordination, hypotension, azotemia. Reversible prostatic atrophy is frequently seen in entire (non-neutered) males.
Spironolactone has an antiandrogenic effect and, therefore, is not recommended in growing dogs.
Monitor renal function before and during treatment. Spironolactone increases the half-life of digoxin its serum levels. Do not administer concomitantly with NSAIDs due to the risk of liver damage, especially in senior animals. Antacids reduce the bioavailability of enalapril.